The Tuscany St Giles Hotel, 129 E. 39th St., New York, N.Y., (212) 686-1600, www.stgiles.com
cost: $339-$595, double occupancy.
drive time: About two hours.
the scoop: The furnishings are plush—just perfect for a laid-back and comfy stay at this contemporary Midtown Manhattan hotel, located in the Murray Hill district, only three blocks from Grand Central Terminal. Accommodations range from studios to loft suites.
amenities: Wi-Fi access is free, and there’s a 24-hour fitness center. Inside the lobby, Audrey Café and Bar serves continental, buffet and à la carte breakfasts, a light dinner menu, and cocktails.
don’t miss: New York’s Little Italy expects to host more than a million people at the 87th annual Feast of San Gennaro, set for Sept. 11-21. This 11-day celebration of the city’s early Italian immigrants features live music, parades, pageants, kids’ activities, and lots of authentic ethnic foods.